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Altered Brain Development Found in Children with Newly Diagnosed Epilepsy: Slowed Development of White Matter Volume Affecting Brain Connectivity

A newly published study reported that children with new/recent onset epilepsy have significantly slowed expansion of white matter volume compared to healthy children over a two year interval.   The reduced white matter volume may affect brain connectivity and influence cognition.   Results of this study conducted by researchers from the University of Wisconsin School of Medicine and Public Health appear in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy.
Can a patient-centred approach to epilepsy improve outcomes?
A Progress Expert Panel Discussion with Ley Sander, Ann Jacoby and John Paul Leach


It is recognised that antiepileptic drug choice is driven by the desire for seizure control, but patient quality of life and consideration of other factors are also important for the treatment of the individual as a whole.

In this expert panel discussion, three specialists discuss the benefits and potential for improved outcomes of a patient-centred approach to epilepsy management.
Adverse Drug Effects in Epileptic Patients Not Correlated with Number of Prescribed Medications

A study published in Epilepsia found that polytherapy with multiple anti-epileptic drugs (AEDs) did not result in greater adverse effects than monotherapy for patients with refractory epilepsy. This observational study also found AED load was not a factor in causing adverse effects, but suggests that individual susceptibility, type of AEDs used, and physicians’ skills determine which patients suffer adverse effects.

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JUST launched: Clinical & Experimental Neuroimmunology!

Get free online access through 2011

Clinical and Experimental Neuroimmunology is an online only, international journal sponsored by the Japanese Society for Neuroimmunology. This new journal publishes the latest clinical and basic science information in the field of neuroscience, basic immunology, clinical neurology and neurovirology, such as:

What drives disease in multiple sclerosis: Inflammation or neurodegeneration? by Hans Lassmann and more

To continue to receive access to this journal, ask your librarian to register for complimentary online access or send recommendation to your library today!

AUTHORS CORNER – Call for Papers

Fast-track publication for papers devoted to understanding, diagnosing, or treating peripheral nerve disorders

Submit your work to the Journal of the Peripheral Nervous System (JPNS). As the official journal of the Peripheral Nerve Society, JPNS publishes original research reports, reviews, letters, and news covering every topic of scientific and clinical relevance to the peripheral nervous system. Articles are expertly peer-reviewed and edited and published fast to ensure subscribers and researchers around the world are kept up to date on the latest research in this area.

For more information on manuscript submission, please visit
http://mc.manuscriptcentral.com/jpns

Must-Read Books
Sleep Disorders in Neurology
Sebastiaan Overeem, Paul Reading

Formulate treatment plans with confidence when you consult Sleep Disorders in Neurology, a helpful overview of both common and rare neurological disorders that are frequently accompanied by significant sleep disturbances.

Atlas of EEG in Critical Care
Lawrence J. Hirsch, Richard P. Brenner

A Primer on Stroke Prevention and Treatment: An overview based on AHA/ASA Guidelines
Edited by Larry B. Goldstein

Stroke and Cerebrovascular Disease in Childhood
Vijeya Ganesan (Editor), Fennella Kirkham (Editor)

The Identification and Treatment of Gait Problems in Cerebral Palsy , 2nd Edition
James R. Gage (Editor), Michael H. Schwartz (Editor), Steven E. Koop (Editor), Tom F. Novacheck (Editor)

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Did you know?
Many of our journals offer Podcasts and are available via iTunes?

This month, access Podcasts from the International Journal of Stroke
Principal investigator Dr Gustavo Saposnik discusses the first stages of the Effectiveness of Virtual Reality Exercises in Stroke Rehabilitation (EVREST) Trial, which was initiated to evaluate the feasibility, safety and efficacy of using the Nintendo Wii gaming virtual reality technology to improve arm recovery in stroke patients. Listen to the podcast

Read the full article in the International Journal of Stroke

Access other IJS podcasts here


Access ends May 31, 2010
A Novel Locus for Familial Migraine on Xp22
Headache: The Journal of Head and Face Pain

Genetic causes of syndromic and non-syndromic autism 
Developmental Medicine & Child Neurology

Idiopathic intracranial hypertension
Acta Neurologica Scandinavica

NEUROPATHIC PAIN
NGX-4010, a High-Concentration Capsaicin Patch, for the Treatment of Postherpetic Neuralgia: A Randomized, Double-Blind,Controlled Study with an Open-Label Extension
Pain Medicine

EFNS/PNS CIDP GUIDELINE
Guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy
Journal of the Peripheral Nervous System

Sample Issues.  Learn what’s new with Annals of Neurology and Neuromodulation: Technology at the Neural Interface

ALZHEIMER REVIEW SERIES from Journal of Cellular and Molecular Medicine Fibrinogen, a possible key player in Alzheimer's disease 
Journal of Thrombosis and Haemostasis

Fibrinogen signal transduction in the nervous system 
Journal of Thrombosis and Haemostasis

Tissue plasminogen activator-mediated PDGF signaling and neurovascular coupling in stroke 
Journal of Thrombosis and Haemostasis

Read these selected Economic Evaluations related to Neurology

From HEED: Health Economics Evaluations Database

HEED equips health professionals with the tools they need to make informed decisions about medicines and other healthcare interventions by selecting, then reviewing published economic studies providing comparative analysis of costs and consequences. For more information about HEED visit http://heed.wiley.com


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World Stroke Organization/7th World Stroke Congress


American Headache Society
June 24-27, Los Angeles, CA

European Congress on Epileptology
June 27-July 1, Rhodes, GREECE

FENS Forum on European Neuroscience
July 2-9, Amsterdam, NETHERLANDS

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