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Neuro-eNewsletter-Masthead_April
 
Dementia in Extreme Elderly Population Expected to Become Epidemic According to The 90+ Study: Oldest Men and Women Experience 18% Annual Dementia Incidence that Increases with Age
University of California researchers found that the incidence rate for all causes of dementia in people age 90 and older is 18.2% annually and significantly increases with age in both men and women. This research, called ”The 90+ Study,” is one of only a few to examine dementia in this age group, and the first to have sufficient participation of centenarians. Findings of the study appear in the February issue of Annals of Neurology, an official publication of the American Neurological Association.
Lacosamide Validated as Promising Therapy for Uncontrolled Partial-Onset Seizures: Second Phase III Trial Demonstrates Safety and Efficacy
A recent multi-center study has confirmed earlier study results that 400 mg/day of lacosamide provides a good balance of efficacy and tolerability for patients with uncontrolled partial-onset seizures (POS), and doses of 600mg/day may provide additional benefit for some patients. Researchers from the Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center, Thomas Jefferson University Medical School, Arkansas Epilepsy Program, Schwarz Biosciences and Johns Hopkins University Hospital conducted this study which is available early online in Epilepsia, the official journal of the International League Against Epilepsy.

Listen to the latest IJS podcasts -
now available to download via iTunes!
EVREST Trial Protocol and discussion of results
Principal investigator Dr Gustavo Saposnik discusses the first stages of the Effectiveness of Virtual Reality Exercises in Stroke Rehabilitation (EVREST) Trial Protocol.
Read the full article in IJS

Burden of Stroke in Argentina - an interview with Professor Conrado Estol
Professor Estol, a neurologist and strokeologist practicing in Argentina, considers the causes of the severe burden of stroke affecting his home country.
Read the full Panorama article in IJS

Dr Stuart Connolly's RE-LY Trial Podcast Interview
The Randomized Evaluation of Long Term Anticoagulant Therapy with dabigatran was initiated to demonstrate the efficacy and safety of dabigatran in patients with non-valvular atrial fibrillation for the prevention of stroke and systemic embolism. The International Journal of Stroke spoke to investigator Dr Stuart Connolly, Professor of Medicine and Director, Division of Cardiology at McMaster University, Hamilton, Canada.

JOURNAL NEWS
The future of neuromodulation and treatment of neurological disorders


The International Neuromodulation Society is pleased to announce the re-launch of its journal, Neuromodulation: Technology at the Neural Interface. Under the leadership of our new Editor-in-Chief, Dr. Robert M. Levy, Neuromodulation has as its mission to become the preeminent journal in the area of neuromodulation, to provide literature reporting state of the art clinical, translational and basic science research in our field and to represent the needs of the broad neuromodulation community, of which neurology is an important part.

To learn more, click on these recent articles:

Editorial: The Future of Neuromodulation

Deep Brain Stimulation, Free Markets and the Scientific Commons: Is It Time to Revisit the Bayh-Dole Act of 1980?

Long-Term, Post-Deep Brain Stimulation Management of a Series of 36 Patients Affected With Refractory Gilles de la Tourette Syndrome

An Analysis of the Components of Pain, Function, and Health-related Quality of Life in Patients with Failed Back Surgery Syndrome Treated with Spinal Cord Stimulation or Conventional Medical Management



JOURNAL NEWS
Award-winning journal offers you limited-time access to select content

EMBO Molecular Medicine is pleased to announce that it is the Winner of the 2009 PROSE Award for best Journal in Science, Technology & Medicine. The PROSE Awards annually recognize the very best in professional and scholarly publishing by bringing attention to distinguished books, journals, and electronic content in over 40 categories.

Download the recently published studies featured below today and read at your leisure. Also be sure to sign up for email table of contents to stay abreast of the latest research.

Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease

A non-enzymatic function of 17ß-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival 

The role of ELOVL1 in very long-chain fatty acid homeostasis and X-linked adrenoleukodystrophy

JOURNAL NEWS
New Neuroimaging and Brain-Mapping focus for:
International Journal of Imaging Systems and Technology
Edited by Z.H. Cho and L. A. Shepp

The International Journal of Imaging Systems and Technology –Neuroimaging and Brain Mapping is a forum for the exchange of ideas and results relevant to imaging systems and their applications in the field of Neuroscience.  The journal now publishes general-interest articles on neuro-imaging.
Continue Reading News Story

Must-Read Books
 
Lecture Notes: Neurology

Lionel Ginsberg

Contains the core neurological information required, whichever branch of clinical medicine you choose.

Reflecting current clinical practice, the latest advances in the diagnosis and management of neurological diseases are concisely covered.

Neurology: A Queen Square Textbook
Edited by Charles Clarke, Robin Howard, Martin Rossor, Simon Shorvon

The Treatment of Epilepsy, 3rd Edition
Edited by Simon Shorvon, Emilio Perucca, Jerome Engel

International Neurology
Edited by Robert P. Lisak, Daniel D. Truong, William Carroll, Roongroj Bhidayasiri

Atlas of EEG in Critical Care
Lawrence J. Hirsch, Richard P. Brenner

A Primer on Stroke Prevention and Treatment: An overview based on AHA/ASA Guidelines
Edited by Larry B. Goldstein

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Did you know?
Independent high-quality evidence for health care decision making in neurology is available from The Cochrane Library – along with Podcasts and a free journal club
Read essential new Cochrane reviews in neurology and the related sciences;

Antiepileptic drugs for the primary and secondary prevention of seizures after stroke

Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy

Interventions for increasing ankle range of motion in patients with neuromuscular disease

Extracranial-intracranial arterial bypass surgery for occlusive carotid artery disease


Podcasts: Every issue we select key Cochrane reviews for accompanying Podcasts. To download please visit - www.cochrane.org/podcasts

Cochrane Journal Club: Finally – no more searching for relevant and interesting papers to discuss at your next journal club meeting! Cochrane Journal Club is a free, monthly publication that introduces a recent Cochrane review, together with relevant background information, a podcast, discussion questions, and downloadable PowerPoint slides containing key figures and tables. You can even contact the review authors with your questions. http://www.cochranejournalclub.com/

Access ends May 31, 2010
Triptan Exposure During Pregnancy and the Risk of Major Congenital Malformations and Adverse Pregnancy Outcomes
Headache: The Journal of Head and Face Pain

Migraine and Obesity: Epidemiology, Mechanisms, and Implications
Headache: The Journal of Head and Face Pain

Prenatal Effects of Antiepileptic Drugs
Epilepsy Currents.

Conferences
European Stroke Conference
May 25-28, Barcelona, SPAIN

European Academy of Childhood Disability
May 27-29, Brussels, BELGIUM

Human Brain Mapping Conference
June 6-10, Barcelona, SPAIN

International Congress of Parkinson's Disease and Movement Disorders
June 13-17, Buenos Aires, ARGENTINA

The European Neurological Society
June 19-23, Berlin, GERMANY

American Headache Society
June 24-27, Los Angeles, CA

European Congress on Epileptology
June 27-July 1, Rhodes, GREECE

FENS Forum on European Neuroscience
July 2-9, Amsterdam, NETHERLANDS
JUST launched: Clinical & Experimental Neuroimmunology!

Get free online access through 2011


Clinical and Experimental Neuroimmunology is an online only, international journal sponsored by the Japanese Society for Neuroimmunology. This new journal publishes the latest clinical and basic science information in the field of neuroscience, basic immunology, clinical neurology and neurovirology, such as:

What drives disease in multiple sclerosis: Inflammation or neurodegeneration? by Hans Lassmann and more
To continue to receive access to this journal, ask your librarian to register for complimentary online access or send recommendation to your library today!

Read these latest articles from the Journal of Cellular and Molecular Medicine

A leaky blood–brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain
Jae K. Ryu, James G. McLarnon

Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology
Kim N. Green

PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease
Milena Morel, Julien Couturier, Claire Lafay-Chebassier, Marc Paccalin, Guylène Page


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